Peer-reviewed Publications

2023

  • Florisela Herrejon Chavez, Hanzhi Luo, Paolo Cifani, Alli Pine, Karen L Chu, Suhasini Joshi, Ersilia Barin, Alexandra Schurer, Mandy Chan, Kathryn Chang, Grace YQ Han, Aspen J Pierson, Michael Xiao, Xuejing Yang, Lindsey M Kuehm, Yuning Hong, Diu T.T. Nguyen, Gabriela Chiosis, Alex Kentsis, Christina Leslie, Ly P Vu, Michael G Kharas. 2023. RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature Communications 14 (1), 2290.
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  • Mlynarczyk, Coraline, Matt Teater, Juhee Pae, Christopher R. Chin, Ling Wang, Theinmozhi Arulraj, Darko Barisic, Antonin Papin, Kenneth B. Hoehn, Ekaterina Kots, Jonatan Ersching, Arnab Bandyopadhyay, Ersilia Barin, Hui Xian Poh, Chiara M. Evans, Amy Chadburn, Zhengming Chen, Hao Shen, Hannah M. Isles, Benedikt Pelzer, Ioanna Tsialta, Ashley S. Doane, Huimin Geng, Muhammad Hassan Rehman, Jonah Melnick, Wyatt Morgan, Diu T.T. Nguyen, Olivier Elemento, Michael G. Kharas, Samie R. Jaffrey, David W. Scott, George Khelashvili, Michael Meyer-Hermann, Gabriel D. Victora, and Ari Melnick. 2023. "Btg1 Mutation Yields Supercompetitive B Cells Primed for Malignant Transformation." Science 379, no. 6629 (2023): eabj7412.

2021

  • Florisela Herrejon Chavez, Paolo Cifani, Alli Pine, Karen L Chu, Ersilia Barin, Alexandra Schurer, Hanzhi Luo, Diu T.T. Nguyen, Alex Kentsis, Christina Leslie, Michael G Kharas, Ly P Vu. 2021. RNA Binding Protein Syncrip Is Required for the Low-Output HSC By Sustaining Proteome Quality. Blood. 138 (Supplement 1): 296.
  • Coraline Mlynarczyk, Matthew Teater, Juhee Pae, Theinmozhi Arulraj, Christopher R Chin, Ling Wang, Jonatan Ersching, Ekaterina Kots, Amy Chadburn, Ersilia Barin, Hui Xian Poh, Hannah M Isles, Chen Zhengming, Hao Shen, Arnab Bandyopadhyay, Kenneth B Hoehn, Diu T.T. Nguyen, Ashley S Doane, Huimin Geng, Muhammad H Rehman, Jonah Melnick, Wyatt Morgan, Olivier Elemento, Michael G Kharas, David W. Scott, Samie R Jaffrey, Michael Meyer-Hermann, George Khelashvili, Gabriel Victora, Ari Melnick. (2021). BTG1 Mutation Promotes Aggressive Lymphoma Development By Lowering the Threshold to MYC Activation and Generating "Super-Competitor" B Cells. Blood (Supplement 1): 359.
  • Camila Prieto*, Diu TT Nguyen*, Zhaoqi Liu, Justin Wheat, Alexendar Perez, Saroj Gourkanti, Timothy Chou, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Arthur Chow, James Taggart, Angela M Savino, Katherina Hoskova, Meera Dhodapkar, Alexandra Schurer, Trevor S Barlowe, Ly P Vu, Christina Leslie, Ulrich Steidl, Raul Rabadan, Michael G Kharas. (2021). Transcriptional control of CBX5 by the RNA binding proteins RBMX and RBMXL1 maintain chromatin state in myeloid leukemia. Nature Cancer 2, 741-757. * Equal contribution.
  • Yuanming Cheng, Wei Xie, Brian F Pickering, Karen L Chu, Angela M Savino, Xuejing Yang, Hanzhi Luo, Diu TT Nguyen, Ersilia Barin, Anthony Velleca, Thomas Rohwetter, Dinshaw J Patel, Samie R Jaffrey and Michael G Kharas. (2021). YTHDC1-m6A-mRNA mediated liquid-liquid phase condensates are required for myeloid leukemia. Cancer Cell 38(7), 958-972.

2020

  • Diu TT Nguyen, Yuheng Lu, Karen L Chu, Xuejing Yang, Sun-Mi Park, Zi-Ning Choo, Christopher R Chin, Camila Prieto, Alexandra Schurer, Ersilia Barin, Angela M Savino, Saroj Gourkanti, Payal Patel, Ly P Vu, Christina Leslie, Michael G Kharas. (2020). HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemia stem cells. Nature Communications 11 (2026).

2019

  • Yuanming Cheng*, Hanzhi Luo*, Franco Izzo*, Brian F Pickering, Diu Nguyen, Robert Myers, Alexandra Schurer, Saroj Gourkanti, Jens C Brüning, Ly P Vu, Samie R Jaffrey, Dan A Landau, Michael G Kharas (2019). RNA methylation maintains hematopoietic stem cell identity and symmetric commitment. Cell Reports 28(7), 1703-1716. * Equal contribution.

2017

  • Ly P Vu*, Brian F Pickering*, Yuanming Cheng*, Sara Zaccara, Diu Nguyen, Gerard Minuesa, Timothy Chou, Arthur Chow, Yogesh Saletore, Matthew MacKay, Jessica Schulman, Christopher Famulare, Minal Patel, Virginia M Klimek, Francine E Garrett-Bakelman, Ari Melnick, Martin Carroll, Christopher E Mason, Samie R Jaffrey, Michael G Kharas. (2017). The N6 methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal and leukemia cells. Nature Medicine 23(11), 1369 (Featured on the cover). * Equal contribution.
  • Diu TT Nguyen, Hsiao Phin J Voon, Barbara Xella, Caroline Scott, David Clynes, Christian Babbs, Helena Ayyub, Jon Kerry, Jacqueline A Sharpe, Jackie A Sloane‐Stanley, Sue Butler, Chris A Fisher, Nicki E Gray, Thomas Jenuwein, Douglas R Higgs, Richard J Gibbons. (2017). The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats. EMBO Report 18(6), 914-928. (Featured on the cover).

Before 2017

  • Marina Bousquet, Diu Nguyen, Cynthia Chen, Lauren Shields, Harvey F Lodish. (2012). miR-125b transforms myeloid cell lines by repressing multiple mRNA targets. Hematologica 97(11), 1713-1721.
  • Huyen T La, Thu T Dang, Quyen H Dao, Diu TT Nguyen, Huan Q Le (2008). Expression of recombinant antibodies specific to CD33 antigen. Journal of Medicine (Vietnamese) (2), 47-52

Other Publications

  • Nguyen DTT, Prieto C, Kharas MG. (2021). New therapeutic targets: RNA binding proteins RBMX/L1 control nascent transcription in leukemia. Behind the paper. Cancer community.
  • Nguyen D, Prieto C, Liu Z, Wheat J, Perez A, Gourkanti, Chou T, Barin E, Chow Arthur, Taggart James, Hoskova K, Dhodapkar M, Schurer A, Barlowe T, Vu L, Leslie C, Steidl U, Rabadan R, Kharas M. (2020). Transcriptional Control of HP1a By the RNA Binding Proteins Rbmx/L1 Maintain Chromatin State in Myeloid Leukemia. Blood. 136. 15-15. 10.1182/blood-2020-142229.
  • Nguyen H., Nguyen L., Nguyen D., Trinh L., Le M., Nguyen T., Tran T., Nguyen N., Le H. Molecular Cell Bilogy (7th edition by Lodish H., et al.) Vietnamese Translation book, Chapter 8, volume 2. (July 2014); Chapter 24, volume 5 (Jan 2019). Tre Publishing House.
  • Diu TT Nguyen, Huyen T La, Trong N Pham, Huan Q Le (2007). Cloning and sequencing Her2/new specific to breast cancer. Proceeding, the 7th National Conference on Life Sciences, Aug 2007.

The DiuNguyen Lab

Centre for Haemato-oncology

Cancer Research UK Barts Centre

Barts and The London School of Medicine and Dentistry

Queen Mary University of London

Barts
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Queen Mary University